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Combination of an autophagy inhibitor with immunoadjuvants and an anti-PD-L1 antibody in multifunctional nanoparticles for enhanced breast cancer immunotherapy

BACKGROUND: The application of combination therapy for cancer treatment is limited due to poor tumor-specific drug delivery and the abscopal effect. METHODS: Here, PD-L1- and CD44-responsive multifunctional nanoparticles were developed using a polymer complex of polyethyleneimine and oleic acid (PEI...

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Detalles Bibliográficos
Autores principales:	Cheng, Yibin, Wang, Caixia, Wang, Huihui, Zhang, Zhiwei, Yang, Xiaopeng, Dong, Yanming, Ma, Lixin, Luo, Jingwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615197/ https://www.ncbi.nlm.nih.gov/pubmed/36303207 http://dx.doi.org/10.1186/s12916-022-02614-8

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