A novel aquaporin-4-associated optic neuritis rat model with severe pathological and functional manifestations

BACKGROUND: Optic neuritis (ON) is a common manifestation of aquaporin-4 (AQP4) antibody seropositive neuromyelitis optica (NMO). The extent of tissue damage is frequently severe, often leading to loss of visual function, and there is no curative treatment for this condition. To develop a novel ther...

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Detalles Bibliográficos
Autores principales: Morita, Yuko, Itokazu, Takahide, Nakanishi, Toru, Hiraga, Shin-ichiro, Yamashita, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615200/
https://www.ncbi.nlm.nih.gov/pubmed/36303157
http://dx.doi.org/10.1186/s12974-022-02623-7

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