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Highlighting Exosomes’ Function in Cardiovascular Diseases
Exosomes, as one of the extracellular vesicles’ subgroups, played an important role in the cell to cell communication. The cargos and surface protein of exosomes have been known to affect the cardiovascular system both positively and negatively in chronic heart failure, ischemic heart disease, and a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Bentham Science Publishers
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615217/ https://www.ncbi.nlm.nih.gov/pubmed/33563169 http://dx.doi.org/10.2174/1573403X17666210204153526 |
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author | Laksono, Sidhi Setianto, Budhi Prawara, Ananta Siddhi Dwiputra, Bambang |
author_facet | Laksono, Sidhi Setianto, Budhi Prawara, Ananta Siddhi Dwiputra, Bambang |
author_sort | Laksono, Sidhi |
collection | PubMed |
description | Exosomes, as one of the extracellular vesicles’ subgroups, played an important role in the cell to cell communication. The cargos and surface protein of exosomes have been known to affect the cardiovascular system both positively and negatively in chronic heart failure, ischemic heart disease, and atherosclerosis. There have been several exosomes that emerged as potential diagnostic and prognostic markers in cardiovascular patients. However, the conditions affecting the patients and the method of isolation should be considered to create a standardized normal value of the exosomes and the components. CPC-derived exosomes, ADSCs-derived exosomes, and telocyte-derived exosomes have been proven to be capable of acting as a therapeutic agent in myocardial infarction models. Exosomes have the potential to become a diagnostic marker, prognostic marker, and therapeutic agent in cardiovascular diseases. |
format | Online Article Text |
id | pubmed-9615217 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Bentham Science Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-96152172023-05-26 Highlighting Exosomes’ Function in Cardiovascular Diseases Laksono, Sidhi Setianto, Budhi Prawara, Ananta Siddhi Dwiputra, Bambang Curr Cardiol Rev Article Exosomes, as one of the extracellular vesicles’ subgroups, played an important role in the cell to cell communication. The cargos and surface protein of exosomes have been known to affect the cardiovascular system both positively and negatively in chronic heart failure, ischemic heart disease, and atherosclerosis. There have been several exosomes that emerged as potential diagnostic and prognostic markers in cardiovascular patients. However, the conditions affecting the patients and the method of isolation should be considered to create a standardized normal value of the exosomes and the components. CPC-derived exosomes, ADSCs-derived exosomes, and telocyte-derived exosomes have been proven to be capable of acting as a therapeutic agent in myocardial infarction models. Exosomes have the potential to become a diagnostic marker, prognostic marker, and therapeutic agent in cardiovascular diseases. Bentham Science Publishers 2022-05-26 2022-05-26 /pmc/articles/PMC9615217/ /pubmed/33563169 http://dx.doi.org/10.2174/1573403X17666210204153526 Text en © 2022 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Laksono, Sidhi Setianto, Budhi Prawara, Ananta Siddhi Dwiputra, Bambang Highlighting Exosomes’ Function in Cardiovascular Diseases |
title | Highlighting Exosomes’ Function in Cardiovascular Diseases |
title_full | Highlighting Exosomes’ Function in Cardiovascular Diseases |
title_fullStr | Highlighting Exosomes’ Function in Cardiovascular Diseases |
title_full_unstemmed | Highlighting Exosomes’ Function in Cardiovascular Diseases |
title_short | Highlighting Exosomes’ Function in Cardiovascular Diseases |
title_sort | highlighting exosomes’ function in cardiovascular diseases |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615217/ https://www.ncbi.nlm.nih.gov/pubmed/33563169 http://dx.doi.org/10.2174/1573403X17666210204153526 |
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