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Highlighting Exosomes’ Function in Cardiovascular Diseases

Exosomes, as one of the extracellular vesicles’ subgroups, played an important role in the cell to cell communication. The cargos and surface protein of exosomes have been known to affect the cardiovascular system both positively and negatively in chronic heart failure, ischemic heart disease, and a...

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Autores principales: Laksono, Sidhi, Setianto, Budhi, Prawara, Ananta Siddhi, Dwiputra, Bambang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615217/
https://www.ncbi.nlm.nih.gov/pubmed/33563169
http://dx.doi.org/10.2174/1573403X17666210204153526
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author Laksono, Sidhi
Setianto, Budhi
Prawara, Ananta Siddhi
Dwiputra, Bambang
author_facet Laksono, Sidhi
Setianto, Budhi
Prawara, Ananta Siddhi
Dwiputra, Bambang
author_sort Laksono, Sidhi
collection PubMed
description Exosomes, as one of the extracellular vesicles’ subgroups, played an important role in the cell to cell communication. The cargos and surface protein of exosomes have been known to affect the cardiovascular system both positively and negatively in chronic heart failure, ischemic heart disease, and atherosclerosis. There have been several exosomes that emerged as potential diagnostic and prognostic markers in cardiovascular patients. However, the conditions affecting the patients and the method of isolation should be considered to create a standardized normal value of the exosomes and the components. CPC-derived exosomes, ADSCs-derived exosomes, and telocyte-derived exosomes have been proven to be capable of acting as a therapeutic agent in myocardial infarction models. Exosomes have the potential to become a diagnostic marker, prognostic marker, and therapeutic agent in cardiovascular diseases.
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spelling pubmed-96152172023-05-26 Highlighting Exosomes’ Function in Cardiovascular Diseases Laksono, Sidhi Setianto, Budhi Prawara, Ananta Siddhi Dwiputra, Bambang Curr Cardiol Rev Article Exosomes, as one of the extracellular vesicles’ subgroups, played an important role in the cell to cell communication. The cargos and surface protein of exosomes have been known to affect the cardiovascular system both positively and negatively in chronic heart failure, ischemic heart disease, and atherosclerosis. There have been several exosomes that emerged as potential diagnostic and prognostic markers in cardiovascular patients. However, the conditions affecting the patients and the method of isolation should be considered to create a standardized normal value of the exosomes and the components. CPC-derived exosomes, ADSCs-derived exosomes, and telocyte-derived exosomes have been proven to be capable of acting as a therapeutic agent in myocardial infarction models. Exosomes have the potential to become a diagnostic marker, prognostic marker, and therapeutic agent in cardiovascular diseases. Bentham Science Publishers 2022-05-26 2022-05-26 /pmc/articles/PMC9615217/ /pubmed/33563169 http://dx.doi.org/10.2174/1573403X17666210204153526 Text en © 2022 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Laksono, Sidhi
Setianto, Budhi
Prawara, Ananta Siddhi
Dwiputra, Bambang
Highlighting Exosomes’ Function in Cardiovascular Diseases
title Highlighting Exosomes’ Function in Cardiovascular Diseases
title_full Highlighting Exosomes’ Function in Cardiovascular Diseases
title_fullStr Highlighting Exosomes’ Function in Cardiovascular Diseases
title_full_unstemmed Highlighting Exosomes’ Function in Cardiovascular Diseases
title_short Highlighting Exosomes’ Function in Cardiovascular Diseases
title_sort highlighting exosomes’ function in cardiovascular diseases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615217/
https://www.ncbi.nlm.nih.gov/pubmed/33563169
http://dx.doi.org/10.2174/1573403X17666210204153526
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