Smoking modulates different secretory subpopulations expressing SARS-CoV-2 entry genes in the nasal and bronchial airways

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SARS-CoV-2 infection and disease severity are influenced by viral entry (VE) gene expression patterns in the airway epithelium. The similarities and differences of VE gene expression (ACE2, TMPRSS2, and CTSL) across nasal and bronchial compartments have not been fully characterized using matched sam...

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Detalles Bibliográficos
Autores principales: Xu, Ke, Shi, Xingyi, Husted, Christopher, Hong, Rui, Wang, Yichen, Ning, Boting, Sullivan, Travis B., Rieger-Christ, Kimberly M., Duan, Fenghai, Marques, Helga, Gower, Adam C., Xiao, Xiaohui, Liu, Hanqiao, Liu, Gang, Duclos, Grant, Platt, Michael, Spira, Avrum E., Mazzilli, Sarah A., Billatos, Ehab, Lenburg, Marc E., Campbell, Joshua D., Beane, Jennifer E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615627/
https://www.ncbi.nlm.nih.gov/pubmed/36307504
http://dx.doi.org/10.1038/s41598-022-17832-6

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