Cargando…

Pathological changes within the cerebral vasculature in Alzheimer’s disease: New perspectives

Cerebrovascular disease underpins vascular dementia (VaD), but structural and functional changes to the cerebral vasculature contribute to disease pathology and cognitive decline in Alzheimer's disease (AD). In this review, we discuss the contribution of cerebral amyloid angiopathy and non‐amyl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fisher, Robert A., Miners, J. Scott, Love, Seth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Invited Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616094/ https://www.ncbi.nlm.nih.gov/pubmed/35289012 http://dx.doi.org/10.1111/bpa.13061

Ejemplares similares

Cerebrovascular disease in ageing and Alzheimer’s disease
por: Love, Seth, et al.
Publicado: (2015)

Mediators of cerebral hypoperfusion and blood‐brain barrier leakiness in Alzheimer’s disease, vascular dementia and mixed dementia
por: Tayler, Hannah, et al.
Publicado: (2021)

Pathophysiology of Hypoperfusion of the Precuneus in Early Alzheimer's Disease
por: Miners, J. Scott, et al.
Publicado: (2015)

Orai1 calcium channels in the vasculature
por: Beech, David J
Publicado: (2012)

Impact of inactivity and exercise on the vasculature in humans
por: Thijssen, Dick H. J., et al.
Publicado: (2009)

The vasculature: a therapeutic target in heart failure?
por: Luxán, Guillermo, et al.
Publicado: (2021)

Systemic infection exacerbates cerebrovascular dysfunction in Alzheimer’s disease
por: Asby, Daniel, et al.
Publicado: (2021)

Differing associations between Aβ accumulation, hypoperfusion, blood–brain barrier dysfunction and loss of PDGFRB pericyte marker in the precuneus and parietal white matter in Alzheimer's disease
por: Miners, J Scott, et al.
Publicado: (2017)

CSF evidence of pericyte damage in Alzheimer’s disease is associated with markers of blood-brain barrier dysfunction and disease pathology
por: Miners, J. S., et al.
Publicado: (2019)

Changes of the retinal and choroidal vasculature in cerebral small vessel disease
por: Geerling, Clara F., et al.
Publicado: (2022)

Invited Review: APOE at the interface of inflammation, neurodegeneration and pathological protein spread in Alzheimer's disease
por: Tzioras, M., et al.
Publicado: (2018)

Impact of vasculature damage on the outcome of spinal cord injury: a novel collagenase-induced model may give new insights into the mechanisms involved
por: Losey, Patrick, et al.
Publicado: (2014)

Emerging perspectives on mitochondrial dysfunction and inflammation in Alzheimer’s disease
por: Yoo, Seung-Min, et al.
Publicado: (2020)

Age-related reduction in brain ACE-2 is not exacerbated by Alzheimer’s disease pathology in mouse models of Alzheimer’s disease
por: MacLachlan, Robert, et al.
Publicado: (2022)

New drug treatments show neuroprotective effects in Alzheimer's and Parkinson's diseases
por: Hölscher, Christian
Publicado: (2014)

The genetics and pathology of mitochondrial disease
por: Alston, Charlotte L, et al.
Publicado: (2016)

Elevated late-life blood pressure may maintain brain oxygenation and slow amyloid-β accumulation at the expense of cerebral vascular damage
por: Tayler, Hannah M, et al.
Publicado: (2023)

A new direction for Alzheimer's research
por: Weinstein, James D.
Publicado: (2018)

Invited Perspective: Long-Lasting Legacy of Banned Contaminants in Alzheimer’s Disease Etiology—Convergence of Epidemiological and Toxicological Findings
por: Cannon, Jason
Publicado: (2022)

Prototyping of cerebral vasculature physical models
por: Khan, Imad S., et al.
Publicado: (2014)

Heterocyclic compounds as key structures for the interaction with old and new targets in Alzheimer’s disease therapy
por: Hiremathad, Asha, et al.
Publicado: (2017)

A critical evaluation of oral baclofen in pediatric patients with cerebral palsy
por: McLaughlin, Matthew J., et al.
Publicado: (2023)

Frontiers in the pathogenesis of Alzheimer’s disease
por: Sambamurti, Kumar, et al.
Publicado: (2009)

The Cerefy(®) Atlas of Cerebral Vasculature
por: Dye, Justin
Publicado: (2010)

The cerefy® Atlas of Cerebral Vasculature
por: Kubben, Pieter L.
Publicado: (2010)

BIN1 Is Decreased in Sporadic but Not Familial Alzheimer’s Disease or in Aging
por: Glennon, Elizabeth B. C., et al.
Publicado: (2013)

Aging Impairs Mitochondrial Function and Mitophagy and Elevates Interleukin 6 Within the Cerebral Vasculature
por: Tyrrell, Daniel J., et al.
Publicado: (2020)

Genetic Risk of Alzheimer's Disease – Sleepless with the Enemy
por: Noyce, Alastair J., et al.
Publicado: (2020)

Plants with less chlorophyll: A global change perspective
por: Genesio, Lorenzo, et al.
Publicado: (2020)

The genetics of mitochondrial disease: dissecting mitochondrial pathology using multi‐omic pipelines
por: Alston, Charlotte L, et al.
Publicado: (2021)

A New Perspective on the Heterogeneity of Cancer Glycolysis
por: Neugent, Michael L., et al.
Publicado: (2018)

Amyloid in the ageing brain: New frameworks and perspectives
por: Hunter, Sally, et al.
Publicado: (2021)

Aβ degradation or cerebral perfusion? Divergent effects of multifunctional enzymes
por: Miners, J. Scott, et al.
Publicado: (2014)

Angiotensin-converting enzyme 2 is reduced in Alzheimer’s disease in association with increasing amyloid-β and tau pathology
por: Kehoe, Patrick Gavin, et al.
Publicado: (2016)

Young blood products: emerging treatment for Alzheimer's disease?
por: Khoury, Rita, et al.
Publicado: (2018)

Alzheimer's disease: the silver tsunami of the 21(st) century
por: Sarkar, Ankita, et al.
Publicado: (2016)

Invited Perspective: Most Affected by Climate Change; Least Studied
por: Ebi, Kristie L., et al.
Publicado: (2021)

Invited Perspective: An Argument for Changing the Reporting Units for Lead in Blood
por: Caravanos, Jack, et al.
Publicado: (2023)

Recapitulating physiological and pathological shear stress and oxygen to model vasculature in health and disease
por: Abaci, Hasan Erbil, et al.
Publicado: (2014)

Cognitive impact of COVID-19: looking beyond the short term
por: Miners, Scott, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ijmke02i3injbpg3268rs9ghjp