Perfusion abnormality in neuronal intranuclear inclusion disease with stroke-like episode: A case report

Neuronal intranuclear inclusion disease (NIID) is a slowly progressive neurodegenerative disease. Some patients with NIID occasionally present with acute symptoms. However, its mechanism remains unclear. We report a patient with NIID who presented with a stroke-like episode. Arterial spin labeling m...

Descripción completa

Detalles Bibliográficos
Autores principales: Kutsuna, Fumiya, Tateishi, Yohei, Yamashita, Kairi, Kanamoto, Tadashi, Hirayama, Takuro, Shima, Tomoaki, Nagaoka, Atsushi, Yoshimura, Shunsuke, Miyazaki, Teiichiro, Sone, Jun, Izumo, Tsuyoshi, Tsujino, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616236/
https://www.ncbi.nlm.nih.gov/pubmed/36324394
http://dx.doi.org/10.1016/j.cccb.2022.100127
Descripción
Sumario:Neuronal intranuclear inclusion disease (NIID) is a slowly progressive neurodegenerative disease. Some patients with NIID occasionally present with acute symptoms. However, its mechanism remains unclear. We report a patient with NIID who presented with a stroke-like episode. Arterial spin labeling magnetic resonance imaging revealed hypoperfusion in the focal cerebral region at the onset while no apparent arterial occlusion was observed. The abnormal perfusion area was normalized 6 days after admission. Therefore, the perfusion abnormality was likely the main cause of acute neurologic deficits in NIID. NIID should be considered in the differential diagnosis of stroke mimics.

Ejemplares similares