High Polygenic Risk Scores Are Associated With Early Age of Onset of Alcohol Use Disorder in Adolescents and Young Adults at Risk

BACKGROUND: Genome-wide association studies have been conducted in alcohol use disorder (AUD), and they permit the use of polygenic risk scores (PRSs), in combination with clinical variables, to predict the onset of AUD in vulnerable populations. METHODS: A total of 2794 adolescent/young adult subje...

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Detalles Bibliográficos
Autores principales: Nurnberger, John I., Wang, Yumin, Zang, Yong, Lai, Dongbing, Wetherill, Leah, Edenberg, Howard J., Aliev, Fazil, Plawecki, Martin H., Chorlian, David, Chan, Grace, Bucholz, Kathleen, Bauer, Lance, Kamarajan, Chella, Salvatore, Jessica E., Kapoor, Manav, Hesselbrock, Victor, Dick, Danielle, Bierut, Laura, McCutcheon, Vivia, Meyers, Jacquelyn L., Porjesz, Bernice, Kramer, John, Kuperman, Samuel, Kinreich, Sivan, Anokhin, Andrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Archival Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616304/
https://www.ncbi.nlm.nih.gov/pubmed/36324664
http://dx.doi.org/10.1016/j.bpsgos.2021.10.007

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