Heterogeneity of treatment effect of interferon-β1b and lopinavir–ritonavir in patients with Middle East respiratory syndrome by cytokine levels

Animal and human data indicate variable effects of interferons in treating coronavirus infections according to inflammatory status and timing of therapy. In this sub-study of the MIRACLE trial (MERS-CoV Infection Treated with a Combination of Lopinavir–Ritonavir and Interferon β-1b), we evaluated th...

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Detalles Bibliográficos
Autores principales: Arabi, Yaseen M., Asiri, Ayed Y., Assiri, Abdullah M., Abdullah, Mashan L., Aljami, Haya A., Balkhy, Hanan H., Al Jeraisy, Majed, Mandourah, Yasser, AlJohani, Sameera, Al Harbi, Shmeylan, Jokhdar, Hani A. Aziz, Deeb, Ahmad M., Memish, Ziad A., Jose, Jesna, Ghazal, Sameeh, Al Faraj, Sarah, Al Mekhlafi, Ghaleb A., Sherbeeni, Nisreen Murad, Elzein, Fatehi Elnour, Hayden, Frederick G., Fowler, Robert A., AlMutairi, Badriah M., Al-Dawood, Abdulaziz, Alharbi, Naif Khalaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616407/
https://www.ncbi.nlm.nih.gov/pubmed/36307462
http://dx.doi.org/10.1038/s41598-022-22742-8

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