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Identification and characterization of circulating immune complexes in IgA nephropathy

The underlying pathology of immunoglobulin A (IgA) nephropathy (IgAN), the most common glomerulonephritis worldwide, is driven by the deposition of immune complexes containing galactose-deficient IgA1 [Tn(+)IgA1] in the glomerular mesangium. Here, we report that novel anti-Tn circulating immune comp...

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Detalles Bibliográficos
Autores principales: Matsumoto, Yasuyuki, Aryal, Rajindra P., Heimburg-Molinaro, Jamie, Park, Simon S., Wever, Walter J., Lehoux, Sylvain, Stavenhagen, Kathrin, van Wijk, Joanna A. E., Van Die, Irma, Chapman, Arlene B., Chaikof, Elliot L., Cummings, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616497/
https://www.ncbi.nlm.nih.gov/pubmed/36306365
http://dx.doi.org/10.1126/sciadv.abm8783