Impact of glycoengineering and antidrug antibodies on the anticancer activity of a plant‐made lectin‐Fc fusion protein

Plants are an efficient production platform for manufacturing glycoengineered monoclonal antibodies and antibody‐like molecules. Avaren‐Fc (AvFc) is a lectin‐Fc fusion protein or lectibody produced in Nicotiana benthamiana, which selectively recognizes cancer‐associated high‐mannose glycans. In this...

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Detalles Bibliográficos
Autores principales: Dent, Matthew, Mayer, Katarina L., Verjan Garcia, Noel, Guo, Haixun, Kajiura, Hiroyuki, Fujiyama, Kazuhito, Matoba, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616523/
https://www.ncbi.nlm.nih.gov/pubmed/35900183
http://dx.doi.org/10.1111/pbi.13902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616523/
https://www.ncbi.nlm.nih.gov/pubmed/35900183
http://dx.doi.org/10.1111/pbi.13902

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