The domiNO effect turns macrophage activation deadly

Macrophage activation is essential for effective immunity to infection but can also contribute to disease through incompletely understood mechanisms. In this issue of Immunity, Simpson et al. reveal that death of activated macrophages integrates extrinsic and intrinsic pathways of apoptosis that con...

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Detalles Bibliográficos
Autores principales: Robertson, Shelly J., Best, Sonja M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616533/
https://www.ncbi.nlm.nih.gov/pubmed/35263563
http://dx.doi.org/10.1016/j.immuni.2022.02.010
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author Robertson, Shelly J.
Best, Sonja M.
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Best, Sonja M.
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description Macrophage activation is essential for effective immunity to infection but can also contribute to disease through incompletely understood mechanisms. In this issue of Immunity, Simpson et al. reveal that death of activated macrophages integrates extrinsic and intrinsic pathways of apoptosis that contribute to damaging host responses.
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spelling pubmed-96165332022-10-31 The domiNO effect turns macrophage activation deadly Robertson, Shelly J. Best, Sonja M. Immunity Preview Macrophage activation is essential for effective immunity to infection but can also contribute to disease through incompletely understood mechanisms. In this issue of Immunity, Simpson et al. reveal that death of activated macrophages integrates extrinsic and intrinsic pathways of apoptosis that contribute to damaging host responses. Cell Press 2022-03-08 2022-03-08 /pmc/articles/PMC9616533/ /pubmed/35263563 http://dx.doi.org/10.1016/j.immuni.2022.02.010 Text en Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Preview
Robertson, Shelly J.
Best, Sonja M.
The domiNO effect turns macrophage activation deadly
title The domiNO effect turns macrophage activation deadly
title_full The domiNO effect turns macrophage activation deadly
title_fullStr The domiNO effect turns macrophage activation deadly
title_full_unstemmed The domiNO effect turns macrophage activation deadly
title_short The domiNO effect turns macrophage activation deadly
title_sort domino effect turns macrophage activation deadly
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616533/
https://www.ncbi.nlm.nih.gov/pubmed/35263563
http://dx.doi.org/10.1016/j.immuni.2022.02.010
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