Population pharmacokinetic/pharmacodynamic study suggests continuous infusion of ceftaroline daily dose in ventilated critical care patients with early-onset pneumonia and augmented renal clearance

OBJECTIVES: Ceftaroline could be suitable to treat early-onset ventilator-associated pneumonia (VAP) because of its antibacterial spectrum. However, augmented renal clearance (ARC) is frequent in ICU patients and may affect ceftaroline pharmacokinetics and efficacy. The objective of the study was to...

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Detalles Bibliográficos
Autores principales: Chauzy, Alexia, Gregoire, Nicolas, Ferrandière, Martine, Lasocki, Sigismond, Ashenoune, Karim, Seguin, Philippe, Boisson, Matthieu, Couet, William, Marchand, Sandrine, Mimoz, Olivier, Dahyot-Fizelier, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616540/
https://www.ncbi.nlm.nih.gov/pubmed/36059138
http://dx.doi.org/10.1093/jac/dkac299

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