Retinoids rescue ceruloplasmin secretion and alleviate oxidative stress in Wilson’s disease-specific hepatocytes

Wilson’s disease (WD) is a copper metabolic disorder caused by a defective ATP7B function. Conventional therapies cause severe side effects and significant variation in efficacy, according to cohort studies. Thus, exploring new therapeutic approaches to prevent progression to liver failure is urgent...

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Detalles Bibliográficos
Autores principales: Song, Dan, Takahashi, Gou, Zheng, Yun-Wen, Matsuo-Takasaki, Mami, Li, Jingyue, Takami, Miho, An, Yuri, Hemmi, Yasuko, Miharada, Natsumi, Fujioka, Tsuyoshi, Noguchi, Michiya, Nakajima, Takashi, Saito, Megumu K, Nakamura, Yukio, Oda, Tatsuya, Miyaoka, Yuichiro, Hayashi, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616579/
https://www.ncbi.nlm.nih.gov/pubmed/35388883
http://dx.doi.org/10.1093/hmg/ddac080

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