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Tumor Fraction Correlates With Detection of Actionable Variants Across > 23,000 Circulating Tumor DNA Samples

Profiling of circulating tumor DNA (ctDNA) is increasingly adopted in the management of solid tumors, concurrent with increased availability of more comprehensive ctDNA panels. However, variable ctDNA shed can result in variable assay sensitivity. We studied the relationship between ctDNA tumor frac...

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Detalles Bibliográficos
Autores principales:	Husain, Hatim, Pavlick, Dean C., Fendler, Bernard J., Madison, Russell W., Decker, Brennan, Gjoerup, Ole, Parachoniak, Christine A., McLaughlin-Drubin, Molly, Erlich, Rachel L., Schrock, Alexa B., Frampton, Garrett M., Das Thakur, Meghna, Oxnard, Geoffrey R., Tukachinsky, Hanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2022
Materias:	Original Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616642/ https://www.ncbi.nlm.nih.gov/pubmed/36265119 http://dx.doi.org/10.1200/PO.22.00261

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