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Macrophages trigger cardiomyocyte proliferation by increasing epicardial vegfaa expression during larval zebrafish heart regeneration

Cardiac injury leads to the loss of cardiomyocytes, which are rapidly replaced by the proliferation of the surviving cells in zebrafish, but not in mammals. In both the regenerative zebrafish and non-regenerative mammals, cardiac injury induces a sustained macrophage response. Macrophages are requir...

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Detalles Bibliográficos
Autores principales: Bruton, Finnius A., Kaveh, Aryan, Ross-Stewart, Katherine M., Matrone, Gianfranco, Oremek, Magdalena E.M., Solomonidis, Emmanouil G., Tucker, Carl S., Mullins, John J., Lucas, Christopher D., Brittan, Mairi, Taylor, Jonathan M., Rossi, Adriano G., Denvir, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616726/
https://www.ncbi.nlm.nih.gov/pubmed/35688158
http://dx.doi.org/10.1016/j.devcel.2022.05.014