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Macrophages trigger cardiomyocyte proliferation by increasing epicardial vegfaa expression during larval zebrafish heart regeneration
Cardiac injury leads to the loss of cardiomyocytes, which are rapidly replaced by the proliferation of the surviving cells in zebrafish, but not in mammals. In both the regenerative zebrafish and non-regenerative mammals, cardiac injury induces a sustained macrophage response. Macrophages are requir...
Autores principales: | Bruton, Finnius A., Kaveh, Aryan, Ross-Stewart, Katherine M., Matrone, Gianfranco, Oremek, Magdalena E.M., Solomonidis, Emmanouil G., Tucker, Carl S., Mullins, John J., Lucas, Christopher D., Brittan, Mairi, Taylor, Jonathan M., Rossi, Adriano G., Denvir, Martin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616726/ https://www.ncbi.nlm.nih.gov/pubmed/35688158 http://dx.doi.org/10.1016/j.devcel.2022.05.014 |
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