Cargando…
Deconstruction of Neurotrypsin Reveals a Multi-factorially Regulated Activity Affecting Myotube Formation and Neuronal Excitability
Neurotrypsin (NT) is a highly specific nervous system multi-domain serine protease best known for its selective processing of the potent synaptic organizer agrin. Its enzymatic activity is thought to influence processes of synaptic plasticity, with its deregulation causing accelerated neuromuscular...
Autores principales: | Canciani, Anselmo, Capitanio, Cristina, Stanga, Serena, Faravelli, Silvia, Scietti, Luigi, Mapelli, Lisa, Soda, Teresa, D’Angelo, Egidio, Kienlen-Campard, Pascal, Forneris, Federico |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616769/ https://www.ncbi.nlm.nih.gov/pubmed/36197591 http://dx.doi.org/10.1007/s12035-022-03056-2 |
Ejemplares similares
-
How to Build and to Protect the Neuromuscular Junction: The Role of the Glial Cell Line-Derived Neurotrophic Factor
por: Stanga, Serena, et al.
Publicado: (2020) -
Specificity of presenilin‐1‐ and presenilin‐2‐dependent γ‐secretases towards substrate processing
por: Stanga, Serena, et al.
Publicado: (2017) -
Stim and Orai proteins in neuronal Ca(2+) signaling and excitability
por: Moccia, Francesco, et al.
Publicado: (2015) -
Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells
por: Decock, Marie, et al.
Publicado: (2016) -
Identifying and Visualizing Macromolecular Flexibility in Structural Biology
por: Palamini, Martina, et al.
Publicado: (2016)