Cargando…
Cilostazol Alleviates NLRP3 Inflammasome–Induced Allodynia/Hyperalgesia in Murine Cerebral Cortex Following Transient Ischemia: Focus on TRPA1/Glutamate and Akt/Dopamine/BDNF/Nrf2 Trajectories
Global cerebral ischemia/reperfusion (I/R) provokes inflammation that augments neuropathic pain. Cilostazol (CLZ) has pleiotropic effects including neuroprotection in several ravaging central disorders; nonetheless, its potential role in transient central ischemic-induced allodynia and hyperalgesia...
Autores principales: | Zaki, Omnia S., Nassar, Noha N., Abdallah, Dalaal M., Safar, Marwa M., Mohammed, Reham A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616778/ https://www.ncbi.nlm.nih.gov/pubmed/36127628 http://dx.doi.org/10.1007/s12035-022-03024-w |
Ejemplares similares
-
The TRPA1 Channel Mediates Mechanical Allodynia and Thermal Hyperalgesia in a Rat Bone Cancer Pain Model
por: Liu, Qiangwei, et al.
Publicado: (2021) -
Upregulation of Glutamate Transporter 1 by Clavulanic Acid Administration and Attenuation of Allodynia and Hyperalgesia in Neuropathic Rats
por: Amin, Bahareh, et al.
Publicado: (2019) -
Neuroprotective effect of liraglutide in an experimental mouse model of multiple sclerosis: role of AMPK/SIRT1 signaling and NLRP3 inflammasome
por: Ammar, Reham A., et al.
Publicado: (2022) -
Involvement of spinal glutamate transporter-1 in the development of mechanical allodynia and hyperalgesia associated with type 2 diabetes
por: Shi, Jinshan, et al.
Publicado: (2016) -
Glial Glutamate Transporter Modulation Prevents Development of Complete Freund’s Adjuvant-Induced Hyperalgesia and Allodynia in Mice
por: Alotaibi, Ghallab, et al.
Publicado: (2023)