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Cilostazol Alleviates NLRP3 Inflammasome–Induced Allodynia/Hyperalgesia in Murine Cerebral Cortex Following Transient Ischemia: Focus on TRPA1/Glutamate and Akt/Dopamine/BDNF/Nrf2 Trajectories

Global cerebral ischemia/reperfusion (I/R) provokes inflammation that augments neuropathic pain. Cilostazol (CLZ) has pleiotropic effects including neuroprotection in several ravaging central disorders; nonetheless, its potential role in transient central ischemic-induced allodynia and hyperalgesia...

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Detalles Bibliográficos
Autores principales: Zaki, Omnia S., Nassar, Noha N., Abdallah, Dalaal M., Safar, Marwa M., Mohammed, Reham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616778/
https://www.ncbi.nlm.nih.gov/pubmed/36127628
http://dx.doi.org/10.1007/s12035-022-03024-w

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