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Genome-scale modeling of Chinese hamster ovary cells by hybrid semi-parametric flux balance analysis
Flux balance analysis (FBA) is currently the standard method to compute metabolic fluxes in genome-scale networks. Several FBA extensions employing diverse objective functions and/or constraints have been published. Here we propose a hybrid semi-parametric FBA extension that combines mechanistic-lev...
Autores principales: | Ramos, João R. C., Oliveira, Gil P., Dumas, Patrick, Oliveira, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616788/ https://www.ncbi.nlm.nih.gov/pubmed/36245012 http://dx.doi.org/10.1007/s00449-022-02795-9 |
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