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Epigallocatechin-3-gallate inhibits osteoclastic differentiation by modulating mitophagy and mitochondrial functions

A natural plant product, epigallocatechin-3-gallate (EGCG), was evaluated for its effectiveness in the regulation of osteoclastogenesis. We found that EGCG inhibited the osteoclast (OC) differentiation in vitro, and in primary bone marrow cells in a dose-dependent manner. Quantitative RT-PCR studies...

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Detalles Bibliográficos
Autores principales:	Sarkar, Jaganmay, Das, Manjusri, Howlader, Md Sariful Islam, Prateeksha, Prateeksha, Barthels, Derek, Das, Hiranmoy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616829/ https://www.ncbi.nlm.nih.gov/pubmed/36307395 http://dx.doi.org/10.1038/s41419-022-05343-1

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