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The N(6)-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity
During erythroid differentiation, the maintenance of genome integrity is key for the success of multiple rounds of cell division. However, molecular mechanisms coordinating the expression of DNA repair machinery in erythroid progenitors are poorly understood. Here, we discover that an RNA N(6)-methy...
Autores principales: | Yoshinaga, Masanori, Han, Kyuho, Morgens, David W., Horii, Takuro, Kobayashi, Ryosuke, Tsuruyama, Tatsuaki, Hia, Fabian, Yasukura, Shota, Kajiya, Asako, Cai, Ting, Cruz, Pedro H. C., Vandenbon, Alexis, Suzuki, Yutaka, Kawahara, Yukio, Hatada, Izuho, Bassik, Michael C., Takeuchi, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616860/ https://www.ncbi.nlm.nih.gov/pubmed/36307435 http://dx.doi.org/10.1038/s41467-022-34078-y |
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