A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing

The experimental need to engineer the genome both in time and space, has led to the development of several photoactivatable Cre recombinase systems. However, the combination of inefficient and non-intentional background recombination has prevented thus far the wide application of these systems in bi...

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Detalles Bibliográficos
Autores principales: Vizoso, Miguel, E. J. Pritchard, Colin, Bombardelli, Lorenzo, van den Broek, Bram, Krimpenfort, Paul, Beijersbergen, Roderick L., Jalink, Kees, van Rheenen, Jacco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616875/
https://www.ncbi.nlm.nih.gov/pubmed/36307419
http://dx.doi.org/10.1038/s41467-022-33863-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616875/
https://www.ncbi.nlm.nih.gov/pubmed/36307419
http://dx.doi.org/10.1038/s41467-022-33863-z

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