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A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing
The experimental need to engineer the genome both in time and space, has led to the development of several photoactivatable Cre recombinase systems. However, the combination of inefficient and non-intentional background recombination has prevented thus far the wide application of these systems in bi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616875/ https://www.ncbi.nlm.nih.gov/pubmed/36307419 http://dx.doi.org/10.1038/s41467-022-33863-z |