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Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA
N6-methyladenosine (m(6)A) is abundant in the mammalian brain and is considered to have a wide range of effects on learning and memory. Here, we found that the upregulated methyltransferase-like protein 16 (METTL16) in the hippocampal tissues of Morris water maze (MWM)-trained mice contributed to im...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616879/ https://www.ncbi.nlm.nih.gov/pubmed/36307396 http://dx.doi.org/10.1038/s41420-022-01220-0 |