Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage

Our previous studies have shown that p53 isoform expression is altered in breast cancer and related to prognosis. In particular, a high ∆40p53:p53α ratio is associated with worse disease-free survival. In this manuscript, the influence of altered Δ40p53 and p53α levels on the response to standard of...

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Detalles Bibliográficos
Autores principales: Steffens Reinhardt, Luiza, Zhang, Xiajie, Groen, Kira, Morten, Brianna C., De Iuliis, Geoffry N., Braithwaite, Antony W., Bourdon, Jean-Christophe, Avery-Kiejda, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616954/
https://www.ncbi.nlm.nih.gov/pubmed/36307393
http://dx.doi.org/10.1038/s41419-022-05349-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616954/
https://www.ncbi.nlm.nih.gov/pubmed/36307393
http://dx.doi.org/10.1038/s41419-022-05349-9

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