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Alterations in the p53 isoform ratio govern breast cancer cell fate in response to DNA damage
Our previous studies have shown that p53 isoform expression is altered in breast cancer and related to prognosis. In particular, a high ∆40p53:p53α ratio is associated with worse disease-free survival. In this manuscript, the influence of altered Δ40p53 and p53α levels on the response to standard of...
Autores principales: | Steffens Reinhardt, Luiza, Zhang, Xiajie, Groen, Kira, Morten, Brianna C., De Iuliis, Geoffry N., Braithwaite, Antony W., Bourdon, Jean-Christophe, Avery-Kiejda, Kelly A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616954/ https://www.ncbi.nlm.nih.gov/pubmed/36307393 http://dx.doi.org/10.1038/s41419-022-05349-9 |
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