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Evidence that conserved essential genes are enriched for pro-longevity factors
At the cellular level, many aspects of aging are conserved across species. This has been demonstrated by numerous studies in simple model organisms like Saccharomyces cerevisiae, Caenorhabdits elegans, and Drosophila melanogaster. Because most genetic screens examine loss of function mutations or de...
Autores principales: | Oz, Naci, Vayndorf, Elena M., Tsuchiya, Mitsuhiro, McLean, Samantha, Turcios-Hernandez, Lesly, Pitt, Jason N., Blue, Benjamin W., Muir, Michael, Kiflezghi, Michael G., Tyshkovskiy, Alexander, Mendenhall, Alexander, Kaeberlein, Matt, Kaya, Alaattin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9616985/ https://www.ncbi.nlm.nih.gov/pubmed/35695982 http://dx.doi.org/10.1007/s11357-022-00604-5 |
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