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Production of CFTR Mutant Gene Model by Homologous Recombination System

OBJECTIVE: The most common mutation in cystic fibrosis (CF), (ΔF508-CFTR), results in impaired protein maturation, folding and transportation to the surface of the cell. As a consequence of impaired protein maturation and/or transport from the extracellular matrix to the cell, different systems are...

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Detalles Bibliográficos
Autores principales:	Rezaee, Hanieh, Salehi, Mohammad, Bandepour, Mojgan, Kalantari, Sima, Hosseini, Sara, Agin, Khosrow Agin, Kezemi, Bahram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royan Institute 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617022/ https://www.ncbi.nlm.nih.gov/pubmed/36259477 http://dx.doi.org/10.22074/cellj.2022.8408

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