Cargando…

Moderate Endurance Training and MitoQ Improve Cardiovascular Function, Oxidative Stress, and Inflammation in Hypertensive Individuals: The Role of miR-21 and miR-222: A Randomized, Double-Blind, Clinical Trial

OBJECTIVE: Hypertension (HTN) is among the leading causes of myocardial infarction, stroke, and kidney disease. The MitoQ supplement is a mitochondrial-targeted antioxidant that attenuates the generation of reactive oxygen species (ROS). miRNAs play an essential role in the pathophysiology of HTN. R...

Descripción completa

Detalles Bibliográficos
Autores principales:	Masoumi-Ardakani, Yaser, Najafipour, Hamid, Nasri, Hamid Reza, Aminizadeh, Soheil, Jafari, Shirin Jafari, Safi, Zohreh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royan Institute 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617024/ https://www.ncbi.nlm.nih.gov/pubmed/36259475 http://dx.doi.org/10.22074/cellj.2022.8089

Ejemplares similares

Effect of Combined Endurance Training and MitoQ on Cardiac Function and Serum Level of Antioxidants, NO, miR-126, and miR-27a in Hypertensive Individuals
por: Masoumi-Ardakani, Yaser, et al.
Publicado: (2022)

Endurance training and MitoQ supplementation improve spatial memory, VEGF expression, and neurogenic factors in hippocampal tissue of rats
por: Zadeh, Hanzaleh Jafari, et al.
Publicado: (2022)

Post-transcriptional Regulation of PCSK9 by miR-191, miR-222, and miR-224
por: Naeli, Parisa, et al.
Publicado: (2017)

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma
por: Zhang, Chun-Zhi, et al.
Publicado: (2010)

Associations between microRNA (miR-25, miR-32, miR-125, and miR-222) polymorphisms and recurrent implantation failure in Korean women
por: Lee, Jeong Yong, et al.
Publicado: (2019)

miR-21, miR-221, and miR-222 upregulation in lung cancer promotes metastasis by reducing oxidative stress and apoptosis
por: Tepebaşı, Muhammet Yusuf, et al.
Publicado: (2023)

Functions of miR-146a and miR-222 in Tumor-associated Macrophages in Breast Cancer
por: Li, Yanshuang, et al.
Publicado: (2015)

Increased expression of miR-155 and miR-222 is associated with lymph node positive status
por: Chernyy, Vladimir, et al.
Publicado: (2018)

Circulating miR-15a and miR-222 as Potential Biomarkers of Type 2 Diabetes
por: Sadeghzadeh, Salman, et al.
Publicado: (2020)

Up-Regulation of miR-21, miR-25, miR-93, and miR-106b in Gastric Cancer
por: Larki, Pegah, et al.
Publicado: (2018)

MiR-222 in Cardiovascular Diseases: Physiology and Pathology
por: Ding, Shengguang, et al.
Publicado: (2017)

Association study of relationships of polymorphisms in the miR-21, miR-26b, miR-221/222 and miR-126 genes with cervical intraepithelial neoplasia and cervical cancer
por: Yang, Jia, et al.
Publicado: (2021)

Expression of MicroRNAs (miR-15b, miR-16, miR-138, miR-221, and miR-222) as Biomarkers of Endothelial Corpus Cavernosum Dysfunction in a Diabetic Alcoholic Murine Model
por: Tiraboschi, Ricardo Brianezi, et al.
Publicado: (2021)

Children’s screen time alters the expression of saliva extracellular miR-222 and miR-146a
por: Vriens, Annette, et al.
Publicado: (2018)

EGFR signaling pathway and related-miRNAs in age-related diseases: the example of miR-221 and miR-222
por: Teixeira, Ana L., et al.
Publicado: (2012)

Evaluation of miR-141, miR-200c, miR-30b Expression and Clinicopathological Features of Bladder Cancer
por: Mahdavinezhad, Ali, et al.
Publicado: (2015)

The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma
por: JIKUZONO, TOMOO, et al.
Publicado: (2013)

MicroRNAs miR-221 and miR-222: a new level of regulation in aggressive breast cancer
por: Shah, Maitri Y, et al.
Publicado: (2011)

Growth inhibitory effects of miR-221 and miR-222 in non-small cell lung cancer cells
por: Yamashita, Ryo, et al.
Publicado: (2015)

miR-221 and miR-222 Simultaneously Target RECK and Regulate Growth and Invasion of Gastric Cancer Cells
por: Liu, Wenneng, et al.
Publicado: (2015)

Prognostic Role of miR-221 and miR-222 Expression in Cancer Patients: A Systematic Review and Meta-Analysis
por: Ravegnini, Gloria, et al.
Publicado: (2019)

Stepwise detection and evaluation reveal miR-10b and miR-222 as a remarkable prognostic pair for glioblastoma
por: Sun, Bo, et al.
Publicado: (2019)

Detection of exosomal miR-18a and miR-222 levels in Egyptian patients with hepatic cirrhosis and hepatocellular carcinoma
por: Elghoroury, Eman A, et al.
Publicado: (2022)

Peripheral blood mononuclear cells expression of miR-200c, miR-125b, miR-27b, miR-203, and miR-155 in patients with significant or insignificant coronary artery stenosis
por: Saadatian, Zahra, et al.
Publicado: (2023)

Study of the Association between microRNA (miR-25T>C, miR-32C>A, miR-125C>T, and miR-222G>T) Polymorphisms and the Risk of Recurrent Pregnancy Loss in Korean Women
por: Lee, Jeong Yong, et al.
Publicado: (2020)

Dietary Improvement during Lactation Normalizes miR-26a, miR-222 and miR-484 Levels in the Mammary Gland, but Not in Milk, of Diet-Induced Obese Rats
por: Pomar, Catalina A., et al.
Publicado: (2022)

Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients
por: Meng, Xiaodan, et al.
Publicado: (2015)

β1-Syntrophin Modulation by miR-222 in mdx Mice
por: De Arcangelis, Valeria, et al.
Publicado: (2010)

Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling
por: Chistiakov, Dmitry A., et al.
Publicado: (2015)

Gastric Carcinogenesis in the miR-222/221 Transgenic Mouse Model
por: Choi, Boram, et al.
Publicado: (2017)

Naturally existing isoforms of miR-222 have distinct functions
por: Yu, Feng, et al.
Publicado: (2017)

miR-222 isoforms are differentially regulated by type-I interferon
por: Nejad, Charlotte, et al.
Publicado: (2018)

Role of miR-221/222 in Tumor Development and the Underlying Mechanism
por: Song, Qian, et al.
Publicado: (2019)

Influence of miR-221/222 on cardiomyocyte calcium handling and function
por: Knyrim, Maria, et al.
Publicado: (2021)

MiR‑221 and miR‑222 regulate cell cycle progression and affect chemosensitivity in breast cancer by targeting ANXA3
por: Kim, Ju-Yeon, et al.
Publicado: (2023)

Evaluating the Differential Expression of miR-146a, miR-222, and miR-9 in Matched Serum and Follicular Fluid of Polycystic Ovary Syndrome Patients: Profiling and Predictive Value
por: Ashrafnezhad, Zhale, et al.
Publicado: (2022)

The Changes of Heart miR-1 and miR-133 Expressions following Physiological Hypertrophy Due to Endurance Training
por: Fathi, Mohammad, et al.
Publicado: (2020)

miR-1, miR-10b, miR-155, and miR-191 are novel regulators of BDNF
por: Varendi, Kärt, et al.
Publicado: (2014)

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients
por: Qiu, Shuwei, et al.
Publicado: (2013)

Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
por: Schee, Kristina, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_3l77fvajdpg685iqgmkcvh7skv