Cargando…

Protocol to generate a patient derived xenograft model of acquired resistance to immunotherapy in humanized mice

Immunotherapy has revolutionized cancer treatment, but preclinical models are required to understand immunotherapy resistance mechanisms underlying patient relapse. This protocol describes how to generate an acquired resistance humanized in vivo model to immunotherapies in patient-derived xenografts...

Descripción completa

Detalles Bibliográficos
Autores principales: Martínez-Sabadell, Alex, Ovejero Romero, Pablo, Arribas, Joaquín, Arenas, Enrique J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617204/
https://www.ncbi.nlm.nih.gov/pubmed/36317178
http://dx.doi.org/10.1016/j.xpro.2022.101712