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Protocol to generate a patient derived xenograft model of acquired resistance to immunotherapy in humanized mice
Immunotherapy has revolutionized cancer treatment, but preclinical models are required to understand immunotherapy resistance mechanisms underlying patient relapse. This protocol describes how to generate an acquired resistance humanized in vivo model to immunotherapies in patient-derived xenografts...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617204/ https://www.ncbi.nlm.nih.gov/pubmed/36317178 http://dx.doi.org/10.1016/j.xpro.2022.101712 |