Frugal alignment-free identification of FLT3-internal tandem duplications with FiLT3r

BACKGROUND: Internal tandem duplications in the FLT3 gene, termed FLT3-ITDs, are useful molecular markers in acute myeloid leukemia (AML) for patient risk stratification and follow-up. FLT3-ITDs are increasingly screened through high-throughput sequencing (HTS) raising the need for robust and effici...

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Detalles Bibliográficos
Autores principales: Boudry, Augustin, Darmon, Sasha, Duployez, Nicolas, Figeac, Martin, Geffroy, Sandrine, Bucci, Maxime, Celli-Lebras, Karine, Duchmann, Matthieu, Joudinaud, Romane, Fenwarth, Laurène, Nibourel, Olivier, Goursaud, Laure, Itzykson, Raphael, Dombret, Hervé, Hunault, Mathilde, Preudhomme, Claude, Salson, Mikaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617311/
https://www.ncbi.nlm.nih.gov/pubmed/36307762
http://dx.doi.org/10.1186/s12859-022-04983-6

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