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Identification of a novel fully human anti-toxic shock syndrome toxin (TSST)-1 single-chain variable fragment antibody averting TSST-1-induced mitogenesis and cytokine secretion

BACKGROUND: Staphylococcal superantigens are virulence factors that help the pathogen escape the immune system and develop an infection. Toxic shock syndrome toxin (TSST)-1 is one of the most studied superantigens whose role in toxic shock syndrome and some particular disorders have been demonstrate...

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Detalles Bibliográficos
Autores principales: Soezi, Mahdieh, Piri-Gavgani, Somayeh, Ghanei, Mostafa, Omrani, Mir Davood, Soltanmohammadi, Behnoush, Bagheri, Kamran Pooshang, Cohan, Reza Ahangari, Vaziri, Farzam, Siadat, Seyed Davar, Fateh, Abolfazl, Khatami, Shohreh, Azizi, Masoumeh, Rahimi-Jamnani, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617332/
https://www.ncbi.nlm.nih.gov/pubmed/36307814
http://dx.doi.org/10.1186/s12896-022-00760-8