Mechanical guidance of self-condensation patterns of differentiating progeny

Spatially controlled self-organization represents a major challenge for organoid engineering. We have developed a mechanically patterned hydrogel for controlling self-condensation process to generate multi-cellular organoids. We first found that local stiffening with intrinsic mechanical gradient (I...

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Detalles Bibliográficos
Autores principales: Matsuzaki, Takahisa, Shimokawa, Yuko, Koike, Hiroyuki, Kimura, Masaki, Kawano, Yuma, Okuma, Nao, Kawamura, Ryuzo, Yoneyama, Yosuke, Furuichi, Yasuro, Hakuno, Fumihiko, Takahashi, Shin-Ichiro, Nakabayashi, Seiichiro, Okamoto, Satoshi, Nakauchi, Hiromitsu, Taniguchi, Hideki, Takebe, Takanori, Yoshikawa, Hiroshi Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617469/
https://www.ncbi.nlm.nih.gov/pubmed/36317160
http://dx.doi.org/10.1016/j.isci.2022.105109

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