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M2 Muscarinic Receptor-Dependent Contractions of Airway Smooth Muscle are Inhibited by Activation of β-Adrenoceptors

Beta-adrenoceptor (β-AR) agonists inhibit cholinergic contractions of airway smooth muscle (ASM), but the underlying mechanisms are unclear. ASM cells express M3 and M2 muscarinic receptors, but the bronchoconstrictor effects of acetylcholine are believed to result from activation of M3Rs, while the...

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Detalles Bibliográficos
Autores principales:	Alkawadri, Tuleen, Wong, Pei Yee, Fong, Zhihui, Lundy, Fionnuala T, McGarvey, Lorcan P, Hollywood, Mark A, Thornbury, Keith D, Sergeant, Gerard P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617473/ https://www.ncbi.nlm.nih.gov/pubmed/36325515 http://dx.doi.org/10.1093/function/zqac050

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