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A Complex Case of Aspergillus Infection of the Brain and Its Future Medical Implications

Aspergillus is a fungal genus found worldwide, which causes infection most commonly in the respiratory system and in other systems, including the central nervous system. Fungal species, such as Aspergillus fumigatus or flavus, are more common in immunocompromised patient populations, such as those t...

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Autores principales: Janardan, Abhishek, Prokhoda, Polina, Razzak, Abrahim N, Jethwa, Trisha, Paudel, Hari R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617596/
https://www.ncbi.nlm.nih.gov/pubmed/36324347
http://dx.doi.org/10.7759/cureus.29756
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author Janardan, Abhishek
Prokhoda, Polina
Razzak, Abrahim N
Jethwa, Trisha
Paudel, Hari R
author_facet Janardan, Abhishek
Prokhoda, Polina
Razzak, Abrahim N
Jethwa, Trisha
Paudel, Hari R
author_sort Janardan, Abhishek
collection PubMed
description Aspergillus is a fungal genus found worldwide, which causes infection most commonly in the respiratory system and in other systems, including the central nervous system. Fungal species, such as Aspergillus fumigatus or flavus, are more common in immunocompromised patient populations, such as those taking immunosuppressants post-transplantation, those on long-term corticosteroids, or those with immunodeficiencies such as AIDS. In this paper, we describe a rare case of aspergillosis that occurred due to a history of taking corticosteroids to treat arthritis pain in a patient with type 2 diabetes. Given the rise in antifungal-resistant species and environmental changes, it is noteworthy for further research to be conducted on new treatment plans and the management of such fungal infections to prepare against opportunistic infections caused by Aspergillus in the future.
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spelling pubmed-96175962022-11-01 A Complex Case of Aspergillus Infection of the Brain and Its Future Medical Implications Janardan, Abhishek Prokhoda, Polina Razzak, Abrahim N Jethwa, Trisha Paudel, Hari R Cureus Internal Medicine Aspergillus is a fungal genus found worldwide, which causes infection most commonly in the respiratory system and in other systems, including the central nervous system. Fungal species, such as Aspergillus fumigatus or flavus, are more common in immunocompromised patient populations, such as those taking immunosuppressants post-transplantation, those on long-term corticosteroids, or those with immunodeficiencies such as AIDS. In this paper, we describe a rare case of aspergillosis that occurred due to a history of taking corticosteroids to treat arthritis pain in a patient with type 2 diabetes. Given the rise in antifungal-resistant species and environmental changes, it is noteworthy for further research to be conducted on new treatment plans and the management of such fungal infections to prepare against opportunistic infections caused by Aspergillus in the future. Cureus 2022-09-29 /pmc/articles/PMC9617596/ /pubmed/36324347 http://dx.doi.org/10.7759/cureus.29756 Text en Copyright © 2022, Janardan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Janardan, Abhishek
Prokhoda, Polina
Razzak, Abrahim N
Jethwa, Trisha
Paudel, Hari R
A Complex Case of Aspergillus Infection of the Brain and Its Future Medical Implications
title A Complex Case of Aspergillus Infection of the Brain and Its Future Medical Implications
title_full A Complex Case of Aspergillus Infection of the Brain and Its Future Medical Implications
title_fullStr A Complex Case of Aspergillus Infection of the Brain and Its Future Medical Implications
title_full_unstemmed A Complex Case of Aspergillus Infection of the Brain and Its Future Medical Implications
title_short A Complex Case of Aspergillus Infection of the Brain and Its Future Medical Implications
title_sort complex case of aspergillus infection of the brain and its future medical implications
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617596/
https://www.ncbi.nlm.nih.gov/pubmed/36324347
http://dx.doi.org/10.7759/cureus.29756
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