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Geneticin shows selective antiviral activity against SARS-CoV-2 by interfering with programmed −1 ribosomal frameshifting
SARS-CoV-2 is currently causing an unprecedented pandemic. While vaccines are massively deployed, we still lack effective large-scale antiviral therapies. In the quest for antivirals targeting conserved structures, we focused on molecules able to bind viral RNA secondary structures. Aminoglycosides...
Autores principales: | Varricchio, Carmine, Mathez, Gregory, Pillonel, Trestan, Bertelli, Claire, Kaiser, Laurent, Tapparel, Caroline, Brancale, Andrea, Cagno, Valeria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617636/ https://www.ncbi.nlm.nih.gov/pubmed/36341734 http://dx.doi.org/10.1016/j.antiviral.2022.105452 |
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