Cargando…

A-Kinase Anchoring Protein 9 Promotes Gastric Cancer Progression as a Downstream Effector of Cadherin 1

BACKGROUND: Genetic studies identified a dozen of frequently mutated genes in gastric cancer, such as cadherin 1 (CDH1) and A-kinase anchoring protein 9 (AKAP9). Of note, genetic alterations including depletion and amplification frameshift mutations of AKAP9 have been observed in 10–15% of gastric c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Qiang, Wu, Youliang, Li, Deguan, Li, Yongxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617730/ https://www.ncbi.nlm.nih.gov/pubmed/36317124 http://dx.doi.org/10.1155/2022/2830634

Ejemplares similares

Receptor Tyrosine Kinases Amplified in Diffuse-Type Gastric Carcinoma: Potential Targeted Therapies and Novel Downstream Effectors
por: Yamaguchi, Hideki, et al.
Publicado: (2022)

Landscape of Druggable Molecular Pathways Downstream of Genomic CDH1/Cadherin-1 Alterations in Gastric Cancer
por: Malpeli, Giorgio, et al.
Publicado: (2022)

Friend or Foe: Regulation, Downstream Effectors of RRAD in Cancer
por: Sun, Zhangyue, et al.
Publicado: (2023)

GPAA1 promotes gastric cancer progression via upregulation of GPI-anchored protein and enhancement of ERBB signalling pathway
por: Zhang, Xiao-Xin, et al.
Publicado: (2019)

The Missing Protein: Is T-Cadherin a Previously Unknown GPI-Anchored Receptor on Platelets?
por: Balatskaya, Maria N., et al.
Publicado: (2021)

MicroRNA-135b Promotes Cancer Progression by Acting as a Downstream Effector of Oncogenic Pathways in Colon Cancer
por: Valeri, Nicola, et al.
Publicado: (2014)

VEGF Mediates Tumor Growth and Metastasis by Affecting the Expression of E-Cadherin and N-Cadherin Promoting Epithelial to Mesenchymal Transition in Gastric Cancer
por: Zhang, Yue, et al.
Publicado: (2023)

Anchoring proteins encounter mitotic kinases
por: Canton, David A., et al.
Publicado: (2013)

The evolutionary history of effectors downstream of Cdc42 and Rac
por: Cotteret, Sophie, et al.
Publicado: (2002)

Ras Downstream Effector GGCT Alleviates Oncogenic Stress
por: He, Zaoke, et al.
Publicado: (2019)

Downstream Effectors of ILK in Cisplatin-Resistant Ovarian Cancer
por: Reyes-González, Jeyshka M., et al.
Publicado: (2020)

Anchors for Effectors: Subversion of Phosphoinositide Lipids by Legionella
por: Hilbi, Hubert, et al.
Publicado: (2011)

Opioid and GABA(B) receptors differentially couple to an adenylyl cyclase/protein kinase A downstream effector after chronic morphine treatment
por: Bagley, Elena E.
Publicado: (2014)

A-Kinase Anchoring Protein 2 Promotes Protection against Myocardial Infarction
por: Maric, Darko, et al.
Publicado: (2021)

A-Kinase Anchoring Protein Targeting of Protein Kinase A and Regulation of HERG Channels
por: Li, Yan, et al.
Publicado: (2008)

Calreticulin enhances gastric cancer metastasis by dimethylating H3K9 in the E-cadherin promoter region mediating by G9a
por: Wang, Lina, et al.
Publicado: (2022)

Cancer Immunotherapy by Targeting IDO1/TDO and Their Downstream Effectors
por: Platten, Michael, et al.
Publicado: (2015)

The erythropoietin receptor is a downstream effector of Klotho-induced cytoprotection
por: Hu, Ming-Chang, et al.
Publicado: (2013)

Signaling Pathways and Downstream Effectors of Host Innate Immunity in Plants
por: Kumar, Jitendra, et al.
Publicado: (2021)

INPP4B exerts a dual role in gastric cancer progression and prognosis
por: Wu, Youliang, et al.
Publicado: (2021)

Clinical and prognostic association of oncogene cadherin 11 in gastric cancer
por: Wang, Qiang, et al.
Publicado: (2020)

Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer
por: Kleiner, Heather E, et al.
Publicado: (2009)

Tissue microarray analysis of eIF4E and its downstream effector proteins in human breast cancer
por: Kleiner, Heather E, et al.
Publicado: (2009)

History and progression of Fat cadherins in health and disease
por: Zhang, Xiaofeng, et al.
Publicado: (2016)

HSV1 MicroRNA Modulation of GPI Anchoring and Downstream Immune Evasion
por: Enk, Jonatan, et al.
Publicado: (2016)

NEDD9 and BCAR1 Negatively Regulate E-Cadherin Membrane Localization, and Promote E-Cadherin Degradation
por: Tikhmyanova, Nadezhda, et al.
Publicado: (2011)

NRP2 transcriptionally regulates its downstream effector WDFY1
por: Dutta, Samikshan, et al.
Publicado: (2016)

Honokiol suppresses lung tumorigenesis by targeting EGFR and its downstream effectors
por: Song, Jung Min, et al.
Publicado: (2016)

Glycosyl phosphatidylinositol--anchored T-cadherin mediates calcium- dependent, homophilic cell adhesion
Publicado: (1992)

Dynamics of ligand-induced, Rac1-dependent anchoring of cadherins to the actin cytoskeleton
por: Lambert, Mireille, et al.
Publicado: (2002)

Structure of HER receptors and intracellular localisation of downstream effector elements gives insight into mechanism of tumour growth promotion
por: Witton, Caroline J
Publicado: (2003)

Silencing of A-Kinase Anchor Protein 4 (AKAP4) Inhibits Proliferation and Progression of Thyroid Cancer
por: Han, Jiakai, et al.
Publicado: (2017)

Legionella pneumophila Exploits PI(4)P to Anchor Secreted Effector Proteins to the Replicative Vacuole
por: Weber, Stefan S, et al.
Publicado: (2006)

Targeting Protein Kinase C Downstream of Growth Factor and Adhesion Signalling
por: Dowling, Catríona M., et al.
Publicado: (2015)

Utilizing proteomic approach to identify nuclear translocation related serine kinase phosphorylation site of GNMT as downstream effector for benzo[a]pyrene
por: Yang, Ming-Hui, et al.
Publicado: (2019)

The formation of ordered nanoclusters controls cadherin anchoring to actin and cell–cell contact fluidity
por: Strale, Pierre-Olivier, et al.
Publicado: (2015)

The formation of ordered nanoclusters controls cadherin anchoring to actin and cell–cell contact fluidity
por: Strale, Pierre-Olivier, et al.
Publicado: (2015)

The synovial cadherin (cadherin-11) promotes intercellular motility
por: Kiener, Hans P, et al.
Publicado: (2007)

High expression of oncogene cadherin-6 correlates with tumor progression and a poor prognosis in gastric cancer
por: Zhao, Zongxian, et al.
Publicado: (2021)

Characterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparum
por: Bandje, Kossiwa, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_nn1a8ne194oh3d6l3043sqpt1r