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Anticancer Effect of Polyphyllin I in Suppressing Stem Cell-Like Properties of Hepatocellular Carcinoma via the AKT/GSK-3β/β-Catenin Signaling Pathway

Polyphyllin I (PPI), also called Chong Lou saponin I, is a steroidal saponin isolated from the rhizome of Paris polyphylla. PPI has been demonstrated to have strong anticancer activity. However, its effect on the stemness of liver cancer stem cells (LCSCs) is not completely understood. Herein, we ai...

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Detalles Bibliográficos
Autores principales: Liao, Mianmian, Du, Haiyan, Wang, Bing, Huang, Jinzhen, Huang, Danping, Tong, Guangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617736/
https://www.ncbi.nlm.nih.gov/pubmed/36317061
http://dx.doi.org/10.1155/2022/4031008

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