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Ectopic expression of OCT4B1 Decreases Fertility Rate and Changes Sperm Parameters in Transgenic Mice

BACKGROUND: The octamer-binding transcription factor-4 (OCT4) is known as an established important regulator of pluripotency, as well as a genetic “master switch” in the self-renewal of embryonic stem and germ cells. OCT4B1, one of the three spliced variants of human OCT4, plays crucial roles in the...

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Detalles Bibliográficos
Autores principales: Naseri, Marzieh, Ranaei Pirmardan, Ehsan, Mowla, Seyed Javad, Shamsara, Mehdi, Movahedin, Mansoreh, Nouri, Saeideh, Nayernia, Karim, Kabir Salmani, Maryam, Shahali, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Genetic Engineering and Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618016/
https://www.ncbi.nlm.nih.gov/pubmed/36381279
http://dx.doi.org/10.30498/ijb.2022.278266.3019