Paraquat is an agonist of STIM1 and increases intracellular calcium levels

Paraquat (PQ) is an efficient herbicide but leads to high mortality with no antidote in mammals. PQ produces reactive oxygen species (ROS), leading to epithelial-mesenchymal transition (EMT) for pulmonary fibrosis in type II alveolar (AT II) cells. Intriguingly, strategies reducing ROS exhibit limit...

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Detalles Bibliográficos
Autores principales: Yang, Wenyu, Tian, Rui, Zhu, Yong, Huang, Peijie, Ma, Xinrun, Meng, Xiaoxiao, Dai, Wentao, Tao, Yiming, Chen, Daonan, Zhang, Jiaxiang, Lu, Jian, Xie, Hui, Jian, Xiangdong, Yang, Zhengfeng, Wang, Ruilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618025/
https://www.ncbi.nlm.nih.gov/pubmed/36310238
http://dx.doi.org/10.1038/s42003-022-04130-0

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