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Opa1-mediated mitochondrial dynamics is important for osteoclast differentiation

Opatic atrophy 1 (Opa1) is a mitochondrial GTPase that regulates mitochondrial fusion and maintenance of cristae architecture. Osteoclasts are mitochondrial rich-cells. However, the role of Opa1 in osteoclasts remains unclear. Here, we demonstrate that Opa1- deficient osteoclast precursor cells do n...

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Detalles Bibliográficos
Autores principales:	Nishikawa, Keizo, Takegami, Hina, Sesaki, Hiromi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Caltech Library 2022
Materias:	New Finding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618030/ https://www.ncbi.nlm.nih.gov/pubmed/36320616 http://dx.doi.org/10.17912/micropub.biology.000650

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