Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation

Development of mammalian auditory epithelium, the organ of Corti, requires precise control of both cell cycle withdrawal and differentiation. Sensory progenitors (prosensory cells) in the cochlear apex exit the cell cycle first but differentiate last. Sonic hedgehog (Shh) signaling is required for t...

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Detalles Bibliográficos
Autores principales: Qin, Tianli, Ho, Chin Chung, Wang, Boshi, Hui, Chi-Chung, Sham, Mai Har
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618052/
https://www.ncbi.nlm.nih.gov/pubmed/36252002
http://dx.doi.org/10.1073/pnas.2206571119

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