Differential interactions of resting, activated, and desensitized states of the α7 nicotinic acetylcholine receptor with lipidic modulators

The α7 nicotinic acetylcholine receptor is a pentameric ligand-gated ion channel that modulates neuronal excitability, largely by allowing Ca(2+) permeation. Agonist binding promotes transition from a resting state to an activated state, and then rapidly to a desensitized state. Recently, cryogenic...

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Detalles Bibliográficos
Autores principales: Zhuang, Yuxuan, Noviello, Colleen M., Hibbs, Ryan E., Howard, Rebecca J., Lindahl, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618078/
https://www.ncbi.nlm.nih.gov/pubmed/36251999
http://dx.doi.org/10.1073/pnas.2208081119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618078/
https://www.ncbi.nlm.nih.gov/pubmed/36251999
http://dx.doi.org/10.1073/pnas.2208081119

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