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Human neutrophil development and functionality are enabled in a humanized mouse model

Mice with a functional human immune system serve as an invaluable tool to study the development and function of the human immune system in vivo. A major technological limitation of all current humanized mouse models is the lack of mature and functional human neutrophils in circulation and tissues. T...

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Detalles Bibliográficos
Autores principales: Zheng, Yunjiang, Sefik, Esen, Astle, John, Karatepe, Kutay, Öz, Hasan H., Solis, Angel G., Jackson, Ruaidhrí, Luo, Hongbo R., Bruscia, Emanuela M., Halene, Stephanie, Shan, Liang, Flavell, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618085/
https://www.ncbi.nlm.nih.gov/pubmed/36269862
http://dx.doi.org/10.1073/pnas.2121077119