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Human neutrophil development and functionality are enabled in a humanized mouse model
Mice with a functional human immune system serve as an invaluable tool to study the development and function of the human immune system in vivo. A major technological limitation of all current humanized mouse models is the lack of mature and functional human neutrophils in circulation and tissues. T...
Autores principales: | Zheng, Yunjiang, Sefik, Esen, Astle, John, Karatepe, Kutay, Öz, Hasan H., Solis, Angel G., Jackson, Ruaidhrí, Luo, Hongbo R., Bruscia, Emanuela M., Halene, Stephanie, Shan, Liang, Flavell, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618085/ https://www.ncbi.nlm.nih.gov/pubmed/36269862 http://dx.doi.org/10.1073/pnas.2121077119 |
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