Cargando…
A COP1-GATA2 axis suppresses AR signaling and prostate cancer
Androgen receptor (AR) signaling is crucial for driving prostate cancer (PCa), the most diagnosed and the second leading cause of death in male patients with cancer in the United States. Androgen deprivation therapy is initially effective in most instances of AR-positive advanced or metastatic PCa....
Autores principales: | Shen, Tao, Dong, Bingning, Meng, Yanling, Moore, David D., Yang, Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618149/ https://www.ncbi.nlm.nih.gov/pubmed/36251994 http://dx.doi.org/10.1073/pnas.2205350119 |
Ejemplares similares
-
Galiellalactone inhibits the STAT3/AR signaling axis and suppresses Enzalutamide-resistant Prostate Cancer
por: Thaper, Daksh, et al.
Publicado: (2018) -
Regulation of COP1 Function by Brassinosteroid Signaling
por: Nieto, Cristina, et al.
Publicado: (2020) -
MAPK6-AKT signaling promotes tumor growth and resistance to mTOR kinase blockade
por: Cai, Qinbo, et al.
Publicado: (2021) -
Analysis of β(2)AR-G(s) and β(2)AR-G(i) complex formation by NMR spectroscopy
por: Ma, Xiuyan, et al.
Publicado: (2020) -
Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain
por: Newton, Kim, et al.
Publicado: (2018)