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Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa

BACKGROUND: Understanding the mechanism of antimicrobial action is critical for improving antibiotic therapy. For the first time, we integrated correlative metabolomics and transcriptomics of Pseudomonas aeruginosa to elucidate the mechanism of synergistic killing of polymyxin–rifampicin combination...

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Detalles Bibliográficos
Autores principales:	Mahamad Maifiah, Mohd Hafidz, Zhu, Yan, Tsuji, Brian T., Creek, Darren J., Velkov, Tony, Li, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618192/ https://www.ncbi.nlm.nih.gov/pubmed/36310165 http://dx.doi.org/10.1186/s12929-022-00874-3

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