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HUSH-mediated HIV silencing is independent of TASOR phosphorylation on threonine 819

BACKGROUND: TASOR, a component of the HUSH repressor epigenetic complex, and SAMHD1, a cellular triphosphohydrolase (dNTPase), are both anti-HIV proteins antagonized by HIV-2/SIVsmm Viral protein X. As a result, the same viral protein is able to relieve two different blocks along the viral life cell...

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Detalles Bibliográficos
Autores principales:	Vauthier, Virginie, Lasserre, Angélique, Morel, Marina, Versapuech, Margaux, Berlioz-Torrent, Clarisse, Zamborlini, Alessia, Margottin-Goguet, Florence, Matkovic, Roy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618200/ https://www.ncbi.nlm.nih.gov/pubmed/36309692 http://dx.doi.org/10.1186/s12977-022-00610-7

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