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Dysregulation of SOX17/NRF2 axis confers chemoradiotherapy resistance and emerges as a novel therapeutic target in esophageal squamous cell carcinoma

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is the sixth leading cause of cancer-associated death worldwide with a dismal overall 5-year survival rate of less than 20%. The standard first-line therapy for advanced ESCC is concomitant chemo-radiation therapy (CCRT); however, patients usuall...

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Detalles Bibliográficos
Autores principales:	Hsieh, Chih-Hsiung, Kuan, Wen-Hui, Chang, Wei-Lun, Kuo, I-Ying, Liu, Hsun, Shieh, Dar-Bin, Liu, Hsuan, Tan, Bertrand, Wang, Yi-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618214/ https://www.ncbi.nlm.nih.gov/pubmed/36310172 http://dx.doi.org/10.1186/s12929-022-00873-4

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